Tailoring the Meso-Structure of Gold Nanoparticles in Keratin-Based Activated Carbon Toward High-Performance Flexible Sensor
Aniruddha Patil, Zhaohui Meng, Ronghui Wu, Liyun Ma, Zijie Xu, Chenyang Shi, Wu Qiu, Qiang Liu, Yifan Zhang, Youhui Lin, Naibo Lin, Xiangyang Liu
Abstract
Abstract Flexible biosensors with high accuracy and reliable operation in detecting pH and uric acid levels in body fluids are fabricated using well-engineered metal-doped porous carbon as electrode material. The gold nanoparticles@N-doped carbon in situ are prepared using wool keratin as both a novel carbon precursor and a stabilizer. The conducting electrode material is fabricated at 500 °C under customized parameters, which mimics A–B type (two different repeating units) polymeric material and displays excellent deprotonation performance (pH sensitivity). The obtained pH sensor exhibits high pH sensitivity of 57 mV/pH unit and insignificant relative standard deviation of 0.088%. Conversely, the composite carbon material with sp 2 structure prepared at 700 °C is doped with nitrogen and gold nanoparticles, which exhibits good conductivity and electrocatalytic activity for uric acid oxidation. The uric acid sensor has linear response over a range of 1–150 µM and a limit of detection 0.1 µM. These results will provide new avenues where biological material will be the best start, which can be useful to target contradictory applications through molecular engineering at mesoscale.