Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy
Xin Xie, Nan Zhang, Xiang Li, He Huang, Cheng Peng, Wei Huang, Leonard J. Foster, Gu He, Bo Han
Topics & Concepts
Hsp90Heat shock proteinChemistryDrug discoveryDrugComputational biologySmall moleculeDrug resistanceCancer therapyCancerPharmacologyBiochemistryBiologyGeneticsGeneMicrobiologyHeat shock proteins researchComputational Drug Discovery MethodsEnzyme Structure and Function