Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras
Akshay D. Takwale, Seunghyun Jo, Yeong Uk Jeon, Hyung Soo Kim, Choong Hoon Shin, Heung Kyoung Lee, Sunjoo Ahn, Chong Ock Lee, Jae Du Ha, Jeong‐Hoon Kim, Jong Yeon Hwang
Topics & Concepts
CereblonAndrogen receptorChemistryLNCaPIn vivoProteolysisProtein degradationProstate cancerProteasomeCancer researchReceptorUbiquitinCell biologyBiochemistryUbiquitin ligaseCancerInternal medicineBiologyMedicineBiotechnologyEnzymeGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsPeptidase Inhibition and Analysis