Translation Phases in Eukaryotes
Sandra Blanchet, Namit Ranjan
Abstract
Protein synthesis in eukaryotes is carried out by 80S ribosomes with the help of many specific translation factors. Translation comprises four major steps: initiation, elongation, termination, and ribosome recycling. In this review, we provide a comprehensive list of translation factors required for protein synthesis in yeast and higher eukaryotes and summarize the mechanisms of each individual phase of eukaryotic translation.
Topics & Concepts
RibosomeTranslation (biology)Protein biosynthesisEukaryotic translationInitiation factorEukaryotic RibosomeComputational biologyInternal ribosome entry siteEIF4EYeastBiologyGeneticsRNAMessenger RNAGeneRNA and protein synthesis mechanismsRNA modifications and cancerPlant and Fungal Interactions Research