Development of poly(ADP-ribose) polymerase inhibitor and immunotherapy combinations: progress, pitfalls, and promises
Melissa Pham, Natalie Y.L. Ngoi, Guang Peng, David S.P. Tan, Timothy A. Yap
Topics & Concepts
ImmunotherapyDrugPoly ADP ribose polymeraseLimitingBlockadeDrug resistancePolymeraseMedicineImmune checkpointCancer researchPharmacologyComputational biologyImmune systemBiologyDNAImmunologyInternal medicineGeneticsMechanical engineeringEngineeringReceptorPARP inhibition in cancer therapyCancer Immunotherapy and BiomarkersCancer therapeutics and mechanisms