Plant-derived exosome-like nanoparticles in tissue repair and regeneration
Canyu Gao, Yang Chen, Xingyue Wen, Ruiying Han, Yuxiang Qin, Sijie Li, Rong Tang, Weikai Zhou, Junyu Zhao, Jianxun Sun, Zhengyong Li, Zhen Tan, Deli Wang, Changchun Zhou
Abstract
This article reviews plant-derived exosome-like nanoparticles (ELNs), and highlights their potential in regenerative medicine. Various extraction techniques, including ultracentrifugation and ultrafiltration, and their impact on ELN purity and yield were discussed. Characterization methods such as microscopy and particle analysis are found to play crucial roles in defining ELN properties. This review is focused on exploring the therapeutic potential of ELNs in tissue repair, immune regulation, and antioxidant activities. Further research and optimization methods for extraction of ELNs to realize clinical potential applications are necessary.