Wee1 kinase inhibitor AZD1775 potentiates CD8+ T cell-dependent antitumour activity via dendritic cell activation following a single high dose of irradiation
Bin Wang, Lin Sun, Zhiyong Yuan, Zhen Tao
Topics & Concepts
Cancer researchWee1CancerPancreatic cancerCancer cellMedicineIn vivoCD8Cell cyclePharmacologyImmune systemImmunologyBiologyInternal medicineCyclin-dependent kinase 1BiotechnologyImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersCAR-T cell therapy research