Characterization and quantification of the phytochemical constituents and anti-inflammatory properties of <i>Lindera aggregata</i>
Songsong Wen, Yongjun Liu, Yulin Liu, Yan Zhao, Xiaoxi Xu, Changchuan Guo, Chong Niu, Weijian Wang, Yuwen Xu, Na Zhang
Abstract
and norisoboldine, isolinderalactone, methyllinderone, and linderin B inhibited the production or expression of nitric oxide, inducible nitric oxide synthase (iNOS), tumor necrosis factor-α, and interleukin-6. Molecular docking of iNOS with isolinderalactone, methyllinderone, and linderin B showed that hydrogen bonds, π-π interactions, and hydrophobic interactions contributed to their iNOS inhibitory effects. The results offer insights that may be instrumental in enhancing the quality control for
Topics & Concepts
PhytochemicalCharacterization (materials science)ChemistryTraditional medicineAnti-inflammatoryBiologyPharmacologyMedicineNanotechnologyBiochemistryMaterials scienceTraditional and Medicinal Uses of AnnonaceaeMoringa oleifera research and applicationsNatural Antidiabetic Agents Studies