A dendritic polyamidoamine supramolecular system composed of pillar[5]arene and azobenzene for targeting drug-resistant colon cancer
Hongyu Liu, Jie Yang, Xiangjie Yan, Chaoqi Li, Mahmoud Elsabahy, Li Chen, Ying‐Wei Yang, Hui Gao
Abstract
experiments demonstrate that Q-P-A@CP[5]A possesses good biocompatibility, excellent antibacterial effect, and CRC treatment capability with negligible side effects. This supramolecular quaternary ammonium system provides an effective treatment method to overcome chemotherapy-resistant cancer caused by bacteria.
Topics & Concepts
Supramolecular chemistryCationic polymerizationMaterials scienceBiocompatibilityAzobenzeneDendrimerAntibacterial activityCombinatorial chemistryNanotechnologyChemistryPolymer chemistryOrganic chemistryBacteriaBiologyMoleculeGeneticsMetallurgyNanoplatforms for cancer theranosticsBacteriophages and microbial interactionsCancer Research and Treatments