Loss of Nrf1 rather than Nrf2 leads to inflammatory accumulation of lipids and reactive oxygen species in human hepatoma cells, which is alleviated by 2-bromopalmitate
Rongzhen Deng, Ze Zheng, Shaofan Hu, Meng Wang, Jing Feng, Peter Mattjus, Zhengwen Zhang, Yiguo Zhang
Topics & Concepts
Reactive oxygen speciesChemistryOxygenCell biologyBiophysicsBiologyOrganic chemistryGenomics, phytochemicals, and oxidative stressLiver Disease Diagnosis and TreatmentPeroxisome Proliferator-Activated Receptors