Tumour evolution inferred by single-cell sequencing
Nicholas E. Navin, Jude Kendall, Jennifer Troge, Peter Andrews, Linda Rodgers, Jeanne McIndoo, Kerry Cook, Asya Stepansky, Dan Levy, Diane Esposito, Lakshmi Muthuswamy, A. Krasnitz, W. Richard McCombie, James Hicks, Michael Wigler
Topics & Concepts
BiologySomatic evolution in cancerSingle cell sequencingMetastasisGenomeGenetic heterogeneityPopulationTumour heterogeneityDNA sequencingSingle-cell analysisCopy-number variationGeneticsCancerEvolutionary biologyCellGenePhenotypeExome sequencingDemographySociologyCancer Genomics and DiagnosticsSingle-cell and spatial transcriptomicsGenomic variations and chromosomal abnormalities