A laser-induced graphene electrochemical immunosensor for label-free CEA monitoring in serum
Guangyuan Wang, Jiayi Chen, Lu Huang, Yiting Chen, Yanxia Li
Abstract
), high selectivity compared with some possible interference, and can be applied in a bovine serum solution without the need of sample labeling and pretreatment. Moreover, the immunosensor is mechanically flexible with minimal change in signal output after bending at different angles. It shows an easy and green electrode preparation method that combines 3D porous structures of graphene, uniform immobilization of Au NPs, binder-free, easy covalent binding of an antibody, and good mechanical properties. Hence, the present method has great potential for applications involving electrochemical biosensors.
Topics & Concepts
GrapheneNanotechnologyElectrochemistryLaserMaterials scienceChromatographyChemistryOpticsElectrodePhysicsPhysical chemistryAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical DetectionElectrochemical sensors and biosensors