Estimates of persistent inward currents increase with the level of voluntary drive in low-threshold motor units of plantar flexor muscles
Lucas B. R. Orssatto, Karen Mackay, Anthony Shield, Raphael Luiz Sakugawa, Anthony J. Blazevich, Gabriel S. Trajano
Abstract
Animal experiments and computational models have shown that motor neurons can amplify the synaptic input they receive via persistent inward currents. Here we show in humans that this amplification varies proportionally to the magnitude of the voluntary drive to the muscle.
Topics & Concepts
Plantar flexionIsometric exerciseMotor unitVastus medialisChemistryTurnoverMotor unit recruitmentElectromyographyAnatomyInternal medicinePhysical medicine and rehabilitationMedicineAnkleEconomicsManagementMuscle activation and electromyography studiesMotor Control and AdaptationNeuroscience and Neural Engineering