Litcius/Paper detail

Discovery of novel benzofuro[3,2-b]quinoline derivatives as dual CDK2/Topo I inhibitors

Yaoguang Huang, Wenwu Liu, Shuoqi Huang, Deping Li, Chang Xu, Xiaowen Jiang, Mingyue Liu, Xin Liu, Chengze Zhu, Limeng Wu, Huanhua Chen, Zihua Xu, Qingchun Zhao

2022Bioorganic Chemistry14 citationsDOI

Topics & Concepts

Cyclin-dependent kinase 2ChemistryQuinolineCell cycleTopoisomeraseRegulatorApoptosisKinaseCell growthCyclin-dependent kinase 1Cancer researchBiochemistryEnzymeBiologyOrganic chemistryGeneCancer therapeutics and mechanismsSynthesis and bioactivity of alkaloidsCancer Mechanisms and Therapy