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Exposure to Bisphenolic Analogues in the Sixth Total Diet Study — China, 2016–2019

Jing Zhang, Kai Yao, Jie Yin, Bing Lyu, Yunfeng Zhao, Jingguang Li, Bing Shao, Yongning Wu

2022China CDC Weekly18 citationsDOIOpen Access PDF

Abstract

What is already known about this topic?: Bisphenol A (BPA) and other bisphenolic compounds (BPs) are proved to pose potential endocrine disrupting properties. The primary source of BP exposure is the diet. European Food Safety Authority (EFSA) established a temporary tolerable daily intake (t-TDI) of BPA 4 μg/kg body weight per day. What is added by this report?: BPs were detected in composite food samples from the Sixth China Total Diet Study (TDS) at percentages of 27.1%-78.5%. The estimated dietary exposure of BPA and bisphenol S (BPS) for an average adult were 18.1 ng/kg body weight per day and 22.2 ng/kg body weight per day, respectively. The main dietary contributors for BPs were cereals, water and beverage, meat as well as vegetables. What are the implications for public health practices?: BP dietary intake poses low risks on the Chinese general population based on the t-TDI set by EFSA. BPS presented a higher exposure level than BPA, which highlights the need to strengthen the surveillance of BP alternatives in foodstuffs.

Topics & Concepts

Tolerable daily intakeBody weightBisphenol AAcceptable daily intakeFood sciencePopulationToxicologyAnimal scienceMedicineBiologyChemistryEnvironmental healthPesticideEndocrinologyEpoxyOrganic chemistryAgronomyEffects and risks of endocrine disrupting chemicalsToxic Organic Pollutants ImpactMicroplastics and Plastic Pollution