A novel phosphorylation site in SARS-CoV-2 nucleocapsid regulates its RNA-binding capacity and phase separation in host cells
Junyu Wu, Yongheng Zhong, Xue Liu, Xiaoyu Lu, Weijie Zeng, Chunyan Wu, Fan Xing, Liu Cao, Fuxiang Zheng, Panpan Hou, Hong Peng, Chunmei Li, Deyin Guo
Topics & Concepts
Host (biology)PhosphorylationRNASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cell biologyCoronavirus disease 2019 (COVID-19)Phase (matter)BiologyVirologyChemistryGeneticsGeneMedicineInfectious disease (medical specialty)Organic chemistryPathologyDiseaseSARS-CoV-2 and COVID-19 ResearchRNA Interference and Gene DeliveryViral Infections and Immunology Research