Resurgence and advancement of photochemical hydrogen atom transfer processes in selective alkane functionalizations
Liang Chang, Shun Wang, Qing An, Linxuan Liu, Hexiang Wang, Yubo Li, Kaixuan Feng, Zhiwei Zuo
Abstract
Nevertheless, challenges in the regulation of radical generation and reaction pathways have created substantial obstacles in the development of diversified alkane functionalizations. In recent years, the application of photoredox catalysis has provided exciting opportunities for alkane C-H functionalization under extremely mild conditions to trigger HAT processes and achieve radical-mediated functionalizations in a more selective manner. Considerable efforts have been devoted to building more efficient and cost-effective photocatalytic systems for sustainable transformations. In this perspective, we highlight the recent development of photocatalytic systems and provide our views on current challenges and future opportunities in this field.