Effectiveness and Safety of Biodegradable Calcium Sulfate Antibiotic Beads as Adjuvant Therapy in Vascular Graft Infections
James B. Doub, Jacqueline Bork, Emily L. Heil, Kristen A. Stafford, Mary Banoub, John Karwowski, Shahab Toursavadkohi
Abstract
This is a retrospective cohort study evaluating the safety and effectiveness of biodegradable calcium sulfate antibiotic beads in vascular graft infections compared with standard of care. No differences in acute kidney injury or hypercalcemia were observed between the cohorts. Recurrence of infection did not occur in the 13-patient bead cohort compared with 14 patients who had recurrence in the 45-patient nonbead cohort with a number needed to treat of 4.0.
Topics & Concepts
MedicineCohortRetrospective cohort studyAntibioticsAdjuvantSurgeryAntibiotic therapyInternal medicineMicrobiologyBiologyInfectious Aortic and Vascular ConditionsVascular Procedures and ComplicationsAortic aneurysm repair treatments