Multifunctional Prussian blue nanozymes alleviate atherosclerosis through inhibiting the inflammation feedback loop
Maochang Xu, Dan Ran, Jian Hu, Jingying Mao, Dehui Qiao, Zongquan Zhang, Xinglong Liang, Li Zhang, Yu Nie, Hong Yang, Xiangyu Zhou, Chunhong Li
Abstract
experimental results demonstrated that BSA@PB/Cur could target plaque locations, significantly efflux the lipid content, and decrease the matrix metalloproteinase expression. This research provides a potential strategy for alleviating the persistent inflammatory feedback loop within the plaque microenvironment for AS treatment.
Topics & Concepts
Prussian blueInflammationMaterials scienceNanotechnologyChemistryMedicineInternal medicineElectrochemistryPhysical chemistryElectrodeAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsNanoplatforms for cancer theranostics