Advanced glycation end-products disrupt brain microvascular endothelial cell barrier: The role of mitochondria and oxidative stress
Anthony Dobi, Sarah Rosanaly, Anne Devin, Pascal Baret, Olivier Meilhac, G. Jean Harry, Christian Lefebvre d’Hellencourt, Philippe Rondeau
Topics & Concepts
GlycationOxidative stressEndothelial stem cellBlood–brain barrierMitochondrionCell biologyReactive oxygen speciesVascular permeabilityChemistryMitochondrial permeability transition poreBarrier functionBiologyBiochemistryProgrammed cell deathEndocrinologyApoptosisCentral nervous systemReceptorIn vitroAdvanced Glycation End Products researchNeurological Disease Mechanisms and TreatmentsBiochemical effects in animals