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Causal association of monocytes with chronic kidney disease and the mediation role of frailty: A study integrating large-scale two-sample Mendelian randomization and single-cell analysis

Cong Zhang, Jielian Deng, Kangjie Li, Guichuan Lai, Hui Liu, Yuan Zhang, Haijiao Zeng, Wenlong Li, Xiaoni Zhong, Yao Wang, Biao Xie

2024Archives of Gerontology and Geriatrics18 citationsDOI

Topics & Concepts

Mendelian randomizationKidney diseaseGenome-wide association studyMedicineDiseaseGenetic associationTranscriptomeInternal medicineMediationBioinformaticsSingle-nucleotide polymorphismGenetic variantsBiologyGeneticsGeneGenotypeGene expressionPolitical scienceLawChronic Kidney Disease and DiabetesDialysis and Renal Disease ManagementFerroptosis and cancer prognosis
Causal association of monocytes with chronic kidney disease and the mediation role of frailty: A study integrating large-scale two-sample Mendelian randomization and single-cell analysis | Litcius