FOXM1-activated SIRT4 inhibits NF-κB signaling and NLRP3 inflammasome to alleviate kidney injury and podocyte pyroptosis in diabetic nephropathy
Xiaohong Xu, Liexiang Zhang, Fei Hua, Ce Zhang, Chi Zhang, Xia Mi, Nan Qin, Junsheng Wang, Aimin Zhu, Zihan Qin, Feihong Zhou
Topics & Concepts
PyroptosisNephrinPodocyteBiologyInflammasomeDiabetic nephropathyCancer researchKidneyDownregulation and upregulationCell biologyCaspase 1NF-κBEndocrinologySignal transductionImmunologyInflammationBiochemistryProteinuriaGeneInflammasome and immune disordersRenal Diseases and GlomerulopathiesHeme Oxygenase-1 and Carbon Monoxide