An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair
Ruorong Yan, Valentina Cigliola, Kelsey A Oonk, Zachary Petrover, Sophia DeLuca, David Wolfson, Andrew M. Vekstein, Michelle A. Mendiola, Garth Devlin, Muath Bishawi, Matthew Gemberling, Tanvi Sinha, Michelle A. Sargent, Allen J. York, Avraham Shakked, Paige DeBenedittis, David C. Wendell, Jianhong Ou, Junsu Kang, Joseph Goldman, Gurpreet S. Baht, Ravi Karra, Adam Williams, Dawn E. Bowles, Aravind Asokan, Eldad Tzahor, Charles A. Gersbach, Jeffery D. Molkentin, Nenad Bursac, Brian L. Black, Kenneth D. Poss
Topics & Concepts
BiologyEnhancerZebrafishGenome editingRegeneration (biology)Cas9CRISPRGenetic enhancementComputational biologyCell biologyGeneGene expressionBioinformaticsGeneticsCongenital heart defects researchCRISPR and Genetic Engineeringinterferon and immune responses