Systemic rewiring of dendritic cells by melanoma-secreted midkine impairs immune surveillance and response to immune checkpoint blockade
Xavier Catena, Marta Contreras-Alcalde, Naiara Juan-Larrea, Daniela Cerezo‐Wallis, Tonantzin G. Calvo, Cynthia Mucientes, David Olmeda, Javier Suárez, Sergio Oterino-Sogo, Lola Martínez, Diego Megı́as, David Sancho, Cristina Tejedo, Susana Frago, Diana Dudziak, Athanasios Seretis, Patrizia Stoitzner, Marı́a S. Soengas
Topics & Concepts
MidkineBlockadeImmune checkpointImmune systemMelanomaCancer researchImmunologyMedicineBiologyImmunotherapyReceptorGrowth factorInternal medicineImmunotherapy and Immune ResponsesChemokine receptors and signalingT-cell and B-cell Immunology