Functional, transcriptional, and microbial shifts associated with healthy pulmonary aging in rhesus macaques
Nicholas S. Rhoades, Michael Davies, Sloan A. Lewis, Isaac R. Cinco, Steven G. Kohama, Luiz E. Bermudez, Kevin Winthrop, Cristina Fuss, Julie A. Mattison, Eliot R. Spindel, Ilhem Messaoudi
Abstract
T cells in the lungs. These data provide insight into age-related changes in the lungs' functional, microbial, and immunological landscape that explain increased prevalence and severity of respiratory diseases in the elderly.
Topics & Concepts
BiologyPulmonary diseaseRhesus macaqueNeuroscienceCell biologyImmunologyMedicineInternal medicineDietary Effects on HealthGut microbiota and healthChronic Obstructive Pulmonary Disease (COPD) Research