Litcius/Paper detail

Discovery of novel acridine-chalcone hybrids with potent DNA binding and antiproliferative activity against MDA-MB-231 and MCF-7 cells

Mária Vilková, Radka Michalková, Martin Kello, Danica Sabolová, Peter Takáč, Z Kudlicková, Monika Garberová, Monika Tvrdoňová, Tibor Béreš, Ján Mojžíš

2022Medicinal Chemistry Research15 citationsDOI

Topics & Concepts

ChalconeChemistryAcridine orangeApoptosisMolecular biologyCell cycleDNA fragmentationCytotoxic T cellFlow cytometryCancer cellIn vitroProgrammed cell deathCell biologyBiochemistryStereochemistryBiologyCancerGeneticsCancer therapeutics and mechanismsSynthesis and biological activityBioactive Compounds and Antitumor Agents