Impact of the Age-Adjusted D-Dimer Cutoff to Exclude Pulmonary Embolism
Helia Robert‐Ebadi, Philippe Robin, Olivier Hügli, Franck Verschuren, Albert Trinh-Duc, Pierre‐Marie Roy, Jeannot Schmidt, Thierry Fumeaux, Guy Meyer, Daniel Hayoz, Pierre‐Nicolas Carron, Pierre‐Yves Salaün, François Sarasin, Olivier Rutschmann, Grégoire Le Gal, Marc Righini
Abstract
Diagnosis of pulmonary embolism (PE) relies on the sequential use of pretest probability (PTP), plasma D-dimer, and computed tomography pulmonary angiography. D-dimer <500 µg/L safely excludes PE in association with a low or intermediate (nonhigh) PTP in approximately one-third of outpatients. To increase the clinical usefulness of D-dimer, a cutoff adjusted to patient’s age was explored. [...]
Topics & Concepts
MedicineD-dimerCutoffPulmonary embolismCardiologyAge adjustmentInternal medicineRadiologyEpidemiologyQuantum mechanicsPhysicsVenous Thromboembolism Diagnosis and ManagementAcute Ischemic Stroke ManagementDiagnosis and Treatment of Venous Diseases