miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke
Runhui Tian, Bo Wu, Cong Fu, Kaimin Guo
Abstract
-dependent MAPK signaling pathway.
Topics & Concepts
Oxidative stressBlockadeMAPK/ERK pathwayMedicineProto-oncogene tyrosine-protein kinase SrcStroke (engine)Signal transductionCognitive impairmentInflammationIschemic strokeNeuroscienceCognitionReceptorIschemiaBiologyInternal medicineCell biologyPsychiatryEngineeringMechanical engineeringNeuroinflammation and Neurodegeneration MechanismsNeurological Disease Mechanisms and TreatmentsMicroRNA in disease regulation