Half-Sandwich Ru(<i>p</i>-cymene) Compounds with Diphosphanes: <i>In Vitro</i> and <i>In Vivo</i> Evaluation As Potential Anticancer Metallodrugs
Oscar A. Lenis-Rojas, M. Paula Robalo, Ana Isabel Tomaz, Alexandra R. Fernandes, Catarina Roma‐Rodrigues, Ricardo G. Teixeira, Fernanda Marques, Mónica Folgueira, Julián Yáñez, Anabel Alba Gonzalez, Martín Salamini-Montemurri, Dawrin Pech-Puch, D. Vázquez-García, M. López-Torres, Alberto Fernández, Jesús J. Fernández
Abstract
concentrations found for the cancer cell models used, highlighting its therapeutic relevance as a drug candidate in cancer chemotherapy.
Topics & Concepts
ChemistryRutheniumCytotoxicityIntercalation (chemistry)StereochemistryReactive oxygen speciesIn vivoApoptosisIn vitroBiochemistryOrganic chemistryBiologyBiotechnologyCatalysisMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsOrganometallic Complex Synthesis and Catalysis