<i>sp</i><sup><i>3</i></sup><i>Bis</i>‐Organometallic Reagents via Catalytic 1,1‐Difunctionalization of Unactivated Olefins
Shang‐Zheng Sun, Laura Talavera, Philipp Spieß, Craig S. Day, Rubén Martı́n
Abstract
Abstract A catalytic 1,1‐difunctionalization of unactivated olefins en route to sp 3 bis ‐organometallic B,B(Si)‐reagents is described. The protocol is characterized by exceptional reaction rates, mild conditions, wide scope, and exquisite selectivity pattern, constituting a new platform to access sp 3 bis ‐organometallics.
Topics & Concepts
ReagentCatalysisChemistryOrganometallic chemistryGroup 2 organometallic chemistryCombinatorial chemistrySelectivityScope (computer science)Medicinal chemistryOrganic chemistryMoleculeComputer scienceProgramming languageCatalytic Cross-Coupling ReactionsOrganoboron and organosilicon chemistryCatalytic C–H Functionalization Methods