The Unfolded Protein Response Modulates a Phosphoinositide-Binding Protein through the IRE1-bZIP60 Pathway
Chao‐Yuan Yu, Kazue Kanehara
Abstract
in the unfolded protein response (UPR). A protein-lipid overlay assay showed specific binding of SVB to phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. SVB is therefore suggested to be the plant-specific phosphoinositide-binding protein whose expression is controlled by the UPR through the IRE1-bZIP60 pathway in Arabidopsis.
Topics & Concepts
Endoplasmic reticulumUnfolded protein responseArabidopsisCell biologyBiologyTunicamycinArabidopsis thalianaMutantGolgi apparatusBiochemistryGeneEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and TherapyCellular transport and secretion