Network pharmacology integrated with experimental validation reveals the regulatory mechanism of action of Hehuan Yin decoction in polycystic ovary syndrome with insulin resistance
Yuanyuan Wu, Shuyu Li, Hui-Qing Zhu, Ziming Zhuang, Meng Shao, Feilong Chen, Chang‐Shun Liu, Qingfa Tang
Topics & Concepts
Polycystic ovaryInsulin resistanceEndocrinologyInternal medicinePI3K/AKT/mTOR pathwayProtein kinase BInsulinInsulin receptorMedicinePharmacologyBiologySignal transductionBiochemistryOvarian function and disordersMedicinal plant effects and applicationsNatural product bioactivities and synthesis