Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity

Connor A. Tsuchida, Shouyue Zhang, Mohammad Saffari Doost, Yuqian Zhao, Jia Wang, Elizabeth O’Brien, Huan Fang, Chengping Li, Danyuan Li, Zhuo-Yan Hai, Jonathan Chuck, Julian Brötzmann, Araz Vartoumian, David Burstein, Xiaowei Chen, Eva Nogales, Jennifer A. Doudna, Junjie Liu