Design of bivalent ligands targeting putative GPCR dimers
Boshi Huang, Celsey M. St. Onge, Hongguang Ma, Yan Zhang
Topics & Concepts
PharmacophoreG protein-coupled receptorComputational biologyBivalent (engine)Drug discoveryChemistryDrugSmall moleculeCombinatorial chemistryNanotechnologyBiologyReceptorStereochemistryPharmacologyBiochemistryMaterials scienceOrganic chemistryMetalReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyChemical Synthesis and Analysis