Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes
Jayanth Chandran, Ekram Ahmed Chowdhury, Michael S. Perkinton, Tanguy Jamier, Daniel Sutton, Shengjia Wu, Claire Dobson, Dhaval K. Shah, Iain P. Chessell, Guy Meno‐Tetang
Topics & Concepts
Transduction (biophysics)Spinal cordLumbar Spinal CordBiologyNeuroscienceGene deliveryThalamusCentral nervous systemStriatumTransgenePharmacologySystemic administrationLumbarGenetic enhancementMedicineAnatomyIn vivoBiotechnologyBiochemistryDopamineGeneVirus-based gene therapy researchHerpesvirus Infections and TreatmentsRNA Interference and Gene Delivery