Extended spectrum beta lactamase (ESBL)-producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> in Indonesia and South East Asian countries: GLASS Data 2018
Sunarno Sunarno, Nelly Puspandari, Fitriana Fitriana, Uly Alfi Nikmah, Hasta Handayani Idrus, Novaria Sari Dewi Panjaitan
Abstract
<abstract> <p>Antimicrobial resistance is the rising global health issue that should not be ignored. This problem needs to be addressed and professionally handled since it is starting to threaten global health, which eventually could lead to disaster. Extended spectrum beta lactamase (ESBL)-producing bacteria were found threatening lives, since most antibiotics were found to not be effective in treating patients with infections caused by those bacteria. ESBL-producing <italic>Escherichia coli</italic> and <italic>Klebsiella pneumoniae</italic> are the two most reported bacteria in causing the bacteremia and nosocomial infections worldwide. In this article, the prevalence of ESBL-producing <italic>E. coli</italic> and <italic>K. pneumoniae</italic> in causing blood stream and urinary tract infections in Indonesia were compared to the neighboring countries based on the global antimicrobial resistance surveillance system performed worldwide by World Health Organization (WHO). In this article, the prevalence of ESBL-producing <italic>E. coli</italic> and <italic>K. pneumoniae</italic> in Indonesia and its neighboring countries were assayed and compared in order to evaluate the antimicrobial resistances. By comparing the prevalence data to the neighboring countries, some insightful evidence and information was served to support improved health in Indonesia. Some hurdles and strategies in combating the antimicrobial resistances were further discussed. Eventually, an alternate solution to overcome the antimicrobial drug resistance should be well-provided, studied and implemented globally.</p> </abstract>