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SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice

Jun Zhu, Pamela M. Quizon, Yingying Wang, Charles Adeniran, Matthew J. Strauss, Ana Catya Jiménez-Torres, Palak Patel, Thomas J. Cirino, Shainnel O. Eans, Haylee R. Hammond, Laure S. Deliscar, Priscilla O'Hara, Surendra Kumar Saini, Edward Ofori, Rakesh H. Vekariya, Sixue Zhang, Omar Moukha‐Chafiq, Theresa Nguyen, Subramaniam Ananthan, Corinne E. Augelli‐Szafran, Chang‐Guo Zhan, Jay P. McLaughlin

2022Neuropharmacology21 citationsDOI

Topics & Concepts

Long-term potentiationDopamine transporterPharmacologyAllosteric regulationConditioned place preferenceAllosteric modulatorDopamine Uptake InhibitorsReuptakeDopamineChemistryDopamine Plasma Membrane Transport ProteinsIn vivoMedicineBiologyEndocrinologyReceptorBiochemistryDopaminergicSerotoninMorphineBiotechnologyHIV Research and TreatmentHIV/AIDS drug development and treatmentRNA Interference and Gene Delivery
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice | Litcius