Antioxidant properties of ethenyl indole: DPPH assay and TDDFT studies
Jagdeep Kumar, Naresh Kumar, Nitin Sati, Prasanta Kumar Hota
Abstract
Ethenyl indole exhibits antioxidant activity in a substituent dependent manner. Ethenyls bearing strong electron withdrawing substituents show weak or no antioxidant activities, whereas ethenyls with electron donating substituents exhibit antioxidant properties comparable to vitamin E.
Topics & Concepts
ChemistryAntioxidantDPPHIndole testSubstituentTime-dependent density functional theoryMedicinal chemistryOrganic chemistryMoleculeFree Radicals and AntioxidantsComputational Drug Discovery MethodsOrganic Chemistry Cycloaddition Reactions