Natural products targeting cancer cell dependency
Changxiang Shi, Eun Ju Yang, Shishi Tao, Guowen Ren, Pui Kei Mou, Joong Sup Shim
Topics & Concepts
Synthetic lethalityDruggabilityDrug discoveryCancerCRISPROlaparibCancer cellComputational biologyBreast cancerCancer researchSuppressorBiologyMedicineBioinformaticsPoly ADP ribose polymeraseGeneticsDNA repairGenePolymeraseCRISPR and Genetic EngineeringCancer Mechanisms and TherapyUbiquitin and proteasome pathways