Photoinitiated stereoselective direct C(sp<sup>2</sup>)–H perfluoroalkylation and difluoroacetylation of enamides
Kai Zhao, Jingyu Guo, Ting Guan, Yingxue Wang, Ji‐Yu Tao, Yu Zhang, Qinghong Zhang, Kun Ni, Teck‐Peng Loh
Abstract
Photoinitiated regio- and stereoselective C(sp<sup>2</sup>)–H perfluoroalkylation and difluoroacetylation of enamides are developed, furnishing biologically and physiologically privileged fluoro-containing enamide scaffolds.
Topics & Concepts
StereoselectivityChemistryStereochemistryOrganic chemistryCatalysisFluorine in Organic ChemistryCarbon dioxide utilization in catalysisSynthesis and Catalytic Reactions