Targeting BRD4 and PI3K signaling pathways for the treatment of medulloblastoma
Bharti Sethi, Virender Kumar, Thilina D. Jayasinghe, Yuxiang Dong, Donald R. Ronning, Haizhen A. Zhong, Donald W. Coulter, Ram I. Mahato
Topics & Concepts
PI3K/AKT/mTOR pathwayMedulloblastomaBRD4Cancer researchChemistryDownregulation and upregulationBromodomainCell biologySonic hedgehogSignal transductionBiologyBiochemistryEpigeneticsGeneProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways