1,8-Naphthyridine Derivatives: A Privileged Scaffold for Versatile Biological Activities
Madhwi Ojha, Divya Yadav, Avinash Kumar, Suman Dasgupta, Rakesh Yadav
Abstract
1, 8- Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic compounds which has garnered the interest of researchers due to its versatile biological activities. It is known to be used as an antimicrobial, anti-psychotic, anti-depressant, anti-convulsant, anti- Alzheimer's, anti-cancer, analgesic, anti-inflammatory, antioxidant, anti-viral, anti-hypertensive, antimalarial, pesticides, anti-platelets, and CB2 receptor agonist, etc. The present review highlights the framework of biological properties of synthesized 1, 8-naphthyridine derivatives developed by various research groups across the globe.
Topics & Concepts
ChemistryAntimicrobialCombinatorial chemistryConvulsantAnalgesicPharmacologyScaffoldBiological activityAnti-inflammatoryAgonistAntioxidantReceptorOrganic chemistryBiochemistryMedicineBiomedical engineeringIn vitroSynthesis and Biological EvaluationPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and biological activity