The effect of pro-/synbiotic supplementation on the brain-derived neurotrophic factor: a systematic review and meta-analysis of randomized controlled trials
Sahar Foshati, Masoumeh Akhlaghi, Siavash Babajafari
Abstract
= 86.6%). Moreover, subgroup analysis showed that the target population, ethnicity and the mean age of participants, the number and type of probiotic strains, administration form, and the dose and duration of pro-/synbiotic supplementation were the potential sources of heterogeneity between RCTs. In conclusion, pro-/synbiotic administration can be considered as a BDNF enhancer and a possible brain booster.
Topics & Concepts
Meta-analysisRandomized controlled trialBrain-derived neurotrophic factorNeurotrophic factorsMedicineSystematic reviewInternal medicinePsychologyBioinformaticsMEDLINEBiologyBiochemistryReceptorAutism Spectrum Disorder ResearchChild Nutrition and Feeding IssuesChild and Adolescent Psychosocial and Emotional Development