New sensitive method for HEPES quantification in <sup>68</sup>Ga-radiopharmaceuticals.
Inês F. Antunes, Gerben M. Franssen, Rolf Zijlma, Peter Laverman, Hendrikus H. Boersma, Philip H. Elsinga
Abstract
BACKGROUND: Ga-radiopharmaceuticals or the use of different synthesis methods could affect the amounts of HEPES. RESULTS: Ga]Ga-PSMA-11. CONCLUSION: . This new analytical system would allow correcting for the maximum injected dose in order not to exceed this amount.
Topics & Concepts
HEPESChemistryChromatographyRadiosynthesisHigh-performance liquid chromatographyThin-layer chromatographyDetection limitBiochemistryNuclear medicinePositron emission tomographyMedicineRadiopharmaceutical Chemistry and ApplicationsMedical Imaging Techniques and ApplicationsRadioactive Decay and Measurement Techniques