Slow conformational dynamics of the human A2A adenosine receptor are temporally ordered
Shushu Wei, Naveen Thakur, Arka Prabha Ray, Beining Jin, Samuel Obeng, Christopher R. McCurdy, Lance Richard McMahon, Hugo Gutiérrez‐de‐Terán, Matthew T. Eddy, Rajan Lamichhane
Topics & Concepts
Total internal reflection fluorescence microscopeChemistryG protein-coupled receptorConformational changeFluorescenceMoleculeMolecular dynamicsBiophysicsProtein dynamicsCrystallographyReceptorStereochemistryPhysicsComputational chemistryBiologyBiochemistryMembraneOrganic chemistryQuantum mechanicsReceptor Mechanisms and SignalingAdenosine and Purinergic SignalingNeuropeptides and Animal Physiology