circPRRC2A promotes angiogenesis and metastasis through epithelial-mesenchymal transition and upregulates TRPM3 in renal cell carcinoma
Wei Li, Feng‐Qiang Yang, Chenmin Sun, Jianhua Huang, Haimin Zhang, Xue Li, Guangchun Wang, Ning Zhang, Jian‐Ping Che, Wentao Zhang, Yang Yan, Xudong Yao, Bo Peng, Junhua Zheng, Min Liu
Abstract
: These findings infer the exciting possibility that circPRRC2A may be exploited as a therapeutic and prognostic target for RCC patients.
Topics & Concepts
Epithelial–mesenchymal transitionCancer researchAngiogenesisMetastasisRenal cell carcinomaOncogenemicroRNAMesenchymal stem cellBiologyIn vivoCancerMedicinePathologyCell cycleInternal medicineGeneBiotechnologyBiochemistryCircular RNAs in diseasesMicroRNA in disease regulation