Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
Jia Song, Ruirui Yang, Jie Chang, Yadan Liu, Cheng-hao Lu, Lifan Chen, Hao Guo, Yinghui Zhang, Zisheng Fan, Jingyi Zhou, Guizhen Zhou, Keke Zhang, Xiaomin Luo, Kaixian Chen, Hualiang Jiang, Sulin Zhang, Ming-yue Zheng
Topics & Concepts
BiochemistryChemistryInflammatory bowel diseaseATP synthaseIn vivoIn vitroPharmacologyBiologyEnzymeMedicinePathologyDiseaseBiotechnologyinterferon and immune responsesImmune Response and InflammationHIV Research and Treatment