Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy
Robert Samstein, Chirag Krishna, Xiaoxiao Ma, Xin Pei, Ken-Wing Lee, Vladimir Makarov, Fengshen Kuo, Jonathan Chung, Raghvendra M. Srivastava, Tanaya A. Purohit, Douglas R. Hoen, Rajarsi Mandal, Jeremy Setton, Wei Wu, Rachna Shah, Besnik Qeriqi, Qing Chang, Sviatoslav M. Kendall, Lior Z. Braunstein, Britta Weigelt, Pedro Blecua, Luc G.T. Morris, Diana Mandelker, Jorge S. Reis‐Filho, Elisa de Stanchina, Simon N. Powell, Timothy A. Chan, Nadeem Riaz
Topics & Concepts
BlockadeAffect (linguistics)ImmunotherapyCancer researchImmune checkpointMedicineTumor microenvironmentOncologyInternal medicinePsychologyCancerTumor cellsReceptorCommunicationCancer Immunotherapy and BiomarkersCancer Genomics and DiagnosticsCAR-T cell therapy research