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TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1

Xiaoyan Ren, Jiangang Yu, Lili Guo, Hong Ma

2020Experimental Cell Research25 citationsDOI

Topics & Concepts

NeuroprotectionDownregulation and upregulationOxidative stressGene knockdownKEAP1BiologyReactive oxygen speciesApoptosisCell biologyAntioxidantPharmacologyTranscription factorEndocrinologyBiochemistryGeneGenomics, phytochemicals, and oxidative stressNeuroinflammation and Neurodegeneration MechanismsMedicinal Plants and Neuroprotection
TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1 | Litcius