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CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker

Arjun K. Mishra, Salman Shahid, S.S. Karade, Pragati Agnihotri, A. V. Kolesnikov, S. Saif Hasan, Roy A. Mariuzza

2023Structure13 citationsDOIOpen Access PDF

Topics & Concepts

Bivalent (engine)Fiducial markerAntibodyChemistryMolecular biologyCrystallographyCancer researchMedicineBiologyImmunologyRadiologyMetalOrganic chemistryMonoclonal and Polyclonal Antibodies ResearchEnzyme Structure and FunctionGlycosylation and Glycoproteins Research
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker | Litcius